Renal failure may result from tubulointerstitial diseases, which are
inflammatory disorders of
the renal tubules and interstitium. After acute tubular necrosis and prerenal AKI, acute
tubulointerstitial nephritis is the third most prevalent cause of acute kidney damage (AKI) in
hospitalized patients. It is primarily brought on by an adverse reaction to medicine. It affects
the renal interstitium and is characterized by an inflammatory infiltration and edema that
manifests for days to months. ATIN causes acute kidney damage; severe cases, postponed
therapy, or continued use of the offending medicine can result in chronic renal disease and
permanent damage. Acute tubulointerstitial nephritis does not have distinct symptoms, hence
it is not apparent until renal failure symptoms appear. ATIN symptoms can appear three to
five days after a second toxic exposure, or they can appear weeks after the first toxic
exposure. The degree of kidney damage and the underlying cause can affect the symptoms of
tubulointerstitial illness. Weakness, reduced appetite, nausea, vomiting, dyspnea, and
variations in urine concentration and volume are typical symptoms.
A combination of the patient's medical history,
physical examination, laboratory testing
A combination of the patient's medical history, physical examination,
laboratory testing, and
imaging examinations is frequently used to diagnose tubulointerstitial illness. To confirm the
diagnosis and determine the degree of kidney injury, a kidney biopsy could also be required.
The degree of kidney damage and the underlying cause
determine how to treat
tubulointerstitial disease.
The degree of kidney damage and the underlying cause determine how to
treat
tubulointerstitial disease. Sometimes treating the underlying disease or getting rid of the
bothersome component may be adequate. In other situations, drugs like immunosuppressants
or corticosteroids might be required to lower inflammation and stop additional kidney injury.
Get in touch with Dr. Vijay Patel, Nephrologist and Kidney Specialist
Doctor for the
treatment of Tubulointerstitial Disease/ Tubulointerstitial Nephritis. He is one of Mumbai's
best kidney specialists as well as one of the best nephrologists in South Mumbai.