Hepatorenal Syndrome
Advanced liver disease patients are at risk for Hepatorenal Syndrome (HRS) A potentially fatal kidney-related disorder. The two conditions most commonly associated with HRS are severe cirrhosis, or liver scarring, and ascites, an abnormal accumulation of fluid in the abdomen that is frequently linked to liver disease. Acute liver failure, or fulminant hepatic failure, as well as other liver disorders, can also cause the syndrome. There are two categories for the hepatorenal syndrome:
- Type 1 (Acute) kidney failure is characterized by a sharp reduction in kidney function that advances rapidly to potentially fatal kidney failure.
- Kidney function declines more gradually in Type 2.
It is currently unknown what causes Hepatorenal Syndrome (HRS)
It is currently unknown what causes Hepatorenal Syndrome (HRS) specifically and how frequently it occurs in patients with severe liver disease. When the kidneys do not receive enough blood flow, renal functions gradually deteriorate. Hepatorenal Syndrome (HRS) nonspecific symptoms include:
Additionally, individuals with Hepatorenal Syndrome (HRS) may experience signs of advanced liver disease, such as:
- An excessive amount of bilirubin in the blood that gives the skin or eyes a yellow tinge (jaundice)
- An unusual accumulation of fluid in the abdomen, known as ascites
- The spleen is swollen (splenomegaly)
- A brief deterioration in brain function caused by hepatic encephalopathy, manifesting as confusion and memory loss